Search flights from Lisbon (LIS) to Santiago (SCL)
Book your plane tickets from Lisbon to Santiago with ease
Cheapest flights to Santiago
The cheapest flights available in the next 60 days – prices are updated regularly
Flying from Lisbon to Santiago: things to know
The most popular route is from Humberto Delgado Airport in Lisbon to Santiago International Airport in Santiago. On average this flight takes 18 hours 47 minutes one way and costs US$1,790 for the round trip.
Most popular route | Humberto Delgado Airport (LIS) to Santiago International Airport (SCL) |
|---|---|
Average flight time | 18 hours 47 minutes |
Average round-trip price | US$1,790 |
Fly from Lisbon to Santiago | 10 airlines |
Reasons to book flights with Booking.com

Great selection
Easily compare flights, airlines and prices – all in one place

No hidden fees
Always know exactly what you’re paying for

Flexibility
Use our flexible plane ticket option to change your dates if needed
Flexible plane ticket options are available for an additional cost on selected airfares
Airlines that fly from Lisbon to Santiago
Airline options may vary according to recently booked flights and your search terms
LATAM
Iberia
Air Europa
TAP Portugal
Air France
Turkish Airlines
Vueling
Air Canada
British Airways
Azul Brazilian Airlines
Frequently asked questions
Fly to more destinations from Lisbon
ParisFrance
LondonUnited Kingdom
MadridSpain
ZürichSwitzerland
AmsterdamNetherlands
BarcelonaSpain
Frankfurt/MainGermany
MunichGermany
Ponta DelgadaPortugal
GenevaSwitzerland
BrusselsBelgium
BerlinGermany
RomeItaly
DüsseldorfGermany
FunchalPortugal
Sao PauloBrazil
PortoPortugal
HamburgGermany
MilanItaly
LuxembourgLuxembourg
CopenhagenDenmark
ManchesterUnited Kingdom
LuandaAngola
WarsawPoland
ViennaAustria
New YorkUnited States
LajesPortugal
